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Adenomatous Polyposis Coli (APC) regulates miR17-92 cluster through β-catenin pathway in colorectal cancer

APC mutation is the most common genetic changes in sporadic colorectal cancer (CRC). Despite deregulations of miRNAs have been frequently reported in this malignancy, APC regulated miRNAs have not been extensively documented. Here, by employing an APC inducible cell line and array analysis, we ident...

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Detalles Bibliográficos
Autores principales: Li, Yajuan, Lauriola, Mattia, Kim, Donghwa, Francesconi, Mirko, D'Uva, Gabriele, Shibata, Dave, Malafa, Mokenge P., Yeatman, Timothy J., Coppola, Domenico, Solmi, Rossella, Cheng, Jin Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960006/
https://www.ncbi.nlm.nih.gov/pubmed/26804172
http://dx.doi.org/10.1038/onc.2015.522