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An update on the genetic causes of central precocious puberty
Central precocious puberty (CPP) is caused by the premature reactivation of the hypothalamic-pituitary-gonadal axis. Genetic, nutritional, and environmental factors play a crucial role in determining pubertal timing. Recently mutations in kisspeptin (KISS1), kisspeptin receptor (KISS1R), and makorin...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Society of Pediatric Endocrinology
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960016/ https://www.ncbi.nlm.nih.gov/pubmed/27462581 http://dx.doi.org/10.6065/apem.2016.21.2.66 |