Using simple models to describe the kinetics of growth, glucose consumption, and monoclonal antibody formation in naive and infliximab producer CHO cells

Despite their practical and commercial relevance, there are few reports on the kinetics of growth and production of Chinese hamster ovary (CHO) cells—the most frequently used host for the industrial production of therapeutic proteins. We characterize the kinetics of cell growth, substrate consumptio...

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Detalles Bibliográficos
Autores principales: López-Meza, Julián, Araíz-Hernández, Diana, Carrillo-Cocom, Leydi Maribel, López-Pacheco, Felipe, Rocha-Pizaña, María del Refugio, Alvarez, Mario Moisés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960177/
https://www.ncbi.nlm.nih.gov/pubmed/26091615
http://dx.doi.org/10.1007/s10616-015-9889-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960177/
https://www.ncbi.nlm.nih.gov/pubmed/26091615
http://dx.doi.org/10.1007/s10616-015-9889-2

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