Cargando…

Using simple models to describe the kinetics of growth, glucose consumption, and monoclonal antibody formation in naive and infliximab producer CHO cells

Despite their practical and commercial relevance, there are few reports on the kinetics of growth and production of Chinese hamster ovary (CHO) cells—the most frequently used host for the industrial production of therapeutic proteins. We characterize the kinetics of cell growth, substrate consumptio...

Descripción completa

Detalles Bibliográficos
Autores principales:	López-Meza, Julián, Araíz-Hernández, Diana, Carrillo-Cocom, Leydi Maribel, López-Pacheco, Felipe, Rocha-Pizaña, María del Refugio, Alvarez, Mario Moisés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960177/ https://www.ncbi.nlm.nih.gov/pubmed/26091615 http://dx.doi.org/10.1007/s10616-015-9889-2

Ejemplares similares

Amino acid consumption in naïve and recombinant CHO cell cultures: producers of a monoclonal antibody
por: Carrillo-Cocom, L. M., et al.
Publicado: (2014)

“Antimicrobial and antiproliferative activity of essential oil, aqueous and ethanolic extracts of Ocimum micranthum Willd leaves”
por: Caamal-Herrera, Isabel O., et al.
Publicado: (2018)

Biocompatibility studies of polyurethane electrospun membranes based on arginine as chain extender
por: Venegas-Cervera, Georgina Alejandra, et al.
Publicado: (2021)

Stress‐induced increase of monoclonal antibody production in CHO cells
por: Schellenberg, Jana, et al.
Publicado: (2022)

Adherence patterns in naïve and prevalent use of infliximab and its biosimilar
por: Alanaeme, Chibuike J., et al.
Publicado: (2022)

Vedolizumab is superior to infliximab in biologic naïve patients with ulcerative colitis
por: Sablich, Renato, et al.
Publicado: (2023)

Biosimilar infliximab versus originator in Crohn’s disease anti-TNF-α naïve and non-naïve patients
por: Kaniewska, Magdalena, et al.
Publicado: (2020)

Multi-omics approach for comparative studies of monoclonal antibody producing CHO cells
por: Orellana, Camila A, et al.
Publicado: (2015)

A descriptive analysis of real-world treatment patterns of innovator (Remicade(®)) and biosimilar infliximab in an infliximab-naïve Turkish population
por: Yazici, Yusuf, et al.
Publicado: (2018)

Retrospective Cohort Study Comparing Infliximab-dyyb and Infliximab in Biologic-Naive Patients With Inflammatory Bowel Disease in the United States
por: Smith, Joshua T, et al.
Publicado: (2021)

Infliximab response associates with radiologic findings in bio-naïve Crohn’s disease
por: Yueying, Chen, et al.
Publicado: (2023)

Inner Speech is not so Simple: A Commentary on Cho and Wu (2013)
por: Moseley, Peter, et al.
Publicado: (2014)

Medium and feed optimization for fed-batch production of a monoclonal antibody in CHO cells
por: Kochanowski, Nadine, et al.
Publicado: (2011)

Kinetic isotope effects and how to describe them
por: Karandashev, Konstantin, et al.
Publicado: (2017)

Selective growth-inhibition of multidrug-resistant CHO-cells by the monoclonal antibody 265/F4.
por: Efferth, T., et al.
Publicado: (1991)

Preliminary evaluation of microcarrier culture for growth and monoclonal antibody production of CHO-K1 cells
por: Rodrigues, M Elisa, et al.
Publicado: (2011)

Reduction in C-terminal amidated species of recombinant monoclonal antibodies by genetic modification of CHO cells
por: Škulj, Mihaela, et al.
Publicado: (2014)

Growth and death kinetics of CHO cells cultivated in continuous bioreactor at various agitation rates
por: Balandras, Frédérique, et al.
Publicado: (2011)

Analyzing Clonal Variation of Monoclonal Antibody-Producing CHO Cell Lines Using an In Silico Metabolomic Platform
por: Ghorbaniaghdam, Atefeh, et al.
Publicado: (2014)

Differential affects of low glucose on the macroheterogeneity and microheterogeneity of glycosylation in CHO-EG2 camelid monoclonal antibodies
por: Liu, Bo, et al.
Publicado: (2013)

Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies
por: Noh, Soo Min, et al.
Publicado: (2018)

Monoclonal antibodies expression improvement in CHO cells by PiggyBac transposition regarding vectors ratios and design
por: Ahmadi, Samira, et al.
Publicado: (2017)

Exploring the limits of conventional small-scale CHO fed-batch for accelerated on demand monoclonal antibody production
por: Mahé, Amélie, et al.
Publicado: (2021)

Novel application of anti‐human Fc nanobody for screening high‐producing CHO cells for monoclonal antibody
por: Zhu, Di, et al.
Publicado: (2022)

Infliximab as rescue therapy in refractory Kawasaki disease
por: Rodríguez-González, Moisés, et al.
Publicado: (2014)

Single use bioreactors for the clinical production of monoclonal antibodies – a study to analyze the performance of a CHO cell line and the quality of the produced monoclonal antibody
por: Diekmann, Sonja, et al.
Publicado: (2011)

Correction: Analyzing Clonal Variation of Monoclonal Antibody-Producing CHO Cell Lines Using an In Silico Metabolomic Platform
Publicado: (2014)

Enhancing and stabilizing monoclonal antibody production by Chinese hamster ovary (CHO) cells with optimized perfusion culture strategies
por: Liang, Kexue, et al.
Publicado: (2023)

Expression of ASFV p17 in CHO cells and identification of one novel epitope using a monoclonal antibody
por: Li, Liwei, et al.
Publicado: (2023)

Epigenetic Regulation of Adipogenic Differentiation by Histone Lysine Demethylation
por: Nic-Can, Geovanny I., et al.
Publicado: (2019)

Mathematical Models to Describe the Kinetic Behavior of Staphylococcus aureus in Jerky
por: Ha, Jimyeong, et al.
Publicado: (2019)

New formulation of the Gompertz equation to describe the kinetics of untreated tumors
por: Castañeda, Antonio Rafael Selva, et al.
Publicado: (2019)

Comparison of Long-term Outcomes of Infliximab versus Adalimumab Treatment in Biologic-Naïve Patients with Ulcerative Colitis
por: Lee, Yong Il, et al.
Publicado: (2021)

Simple models describing the time-evolution of luminosity in hadron colliders
por: Giovannozzi, M
Publicado: (2014)

Ten simple rules for describing a new (parasite) species
por: Šlapeta, Jan
Publicado: (2013)

Describing dengue epidemics: Insights from simple mechanistic models
por: Aguiar, Maíra, et al.
Publicado: (2012)

Spitz nevus and infliximab: association or coincidence?()()
por: Queirós, Catarina Soares, et al.
Publicado: (2020)

Effects of Iron-Oxide Nanoparticle Surface Chemistry on Uptake Kinetics and Cytotoxicity in CHO-K1 Cells
por: Hanot, Camille C., et al.
Publicado: (2015)

Construction of a gene knockout CHO cell line using a simple gene targeting method
por: Aga, Marina, et al.
Publicado: (2015)

Understanding the impact of different bioprocess conditions on monoclonal antibody glycosylation in CHO cell cultures through experimental and computational analyses
por: Sou, Si N, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8fflahfjec04ecfajd3nrnvu80