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Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster
The Amyloid precursor protein (APP) has mainly been investigated in connection with its role in Alzheimer’s Disease (AD) due to its cleavage resulting in the production of the Aβ peptides that accumulate in the plaques characteristic for this disease. However, APP is an evolutionary conserved protei...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960247/ https://www.ncbi.nlm.nih.gov/pubmed/27507933 http://dx.doi.org/10.3389/fnmol.2016.00061 |