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Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster

The Amyloid precursor protein (APP) has mainly been investigated in connection with its role in Alzheimer’s Disease (AD) due to its cleavage resulting in the production of the Aβ peptides that accumulate in the plaques characteristic for this disease. However, APP is an evolutionary conserved protei...

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Detalles Bibliográficos
Autores principales: Cassar, Marlène, Kretzschmar, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960247/
https://www.ncbi.nlm.nih.gov/pubmed/27507933
http://dx.doi.org/10.3389/fnmol.2016.00061

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