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Oxidative Stress-Activated NHE1 Is Involved in High Glucose-Induced Apoptosis in Renal Tubular Epithelial Cells

PURPOSE: Diabetic nephropathy (DN) is a prevalent chronic microvascular complication of diabetes mellitus involving disturbances in electrolytes and the acid-base balance caused by a disorder of glucose metabolism. NHE1 is a Na(+)/H(+) exchanger responsible for keeping intracellular pH (pH(i)) balan...

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Detalles Bibliográficos
Autores principales: Wu, Yiqing, Zhang, Min, Liu, Rui, Zhao, Chunjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960394/
https://www.ncbi.nlm.nih.gov/pubmed/27401659
http://dx.doi.org/10.3349/ymj.2016.57.5.1252