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Oxidative Stress-Activated NHE1 Is Involved in High Glucose-Induced Apoptosis in Renal Tubular Epithelial Cells
PURPOSE: Diabetic nephropathy (DN) is a prevalent chronic microvascular complication of diabetes mellitus involving disturbances in electrolytes and the acid-base balance caused by a disorder of glucose metabolism. NHE1 is a Na(+)/H(+) exchanger responsible for keeping intracellular pH (pH(i)) balan...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960394/ https://www.ncbi.nlm.nih.gov/pubmed/27401659 http://dx.doi.org/10.3349/ymj.2016.57.5.1252 |