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Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma

Osteosarcoma patient survival has remained stagnant for 30 years. Novel therapeutic approaches are needed to improve outcomes. We examined the expression of Programmed Death Ligand 1 (PD-L1) and defined the tumor immune microenvironment to assess the prognostic utility in osteosarcoma. PD-L1 express...

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Detalles Bibliográficos
Autores principales: Koirala, Pratistha, Roth, Michael E., Gill, Jonathan, Piperdi, Sajida, Chinai, Jordan M., Geller, David S., Hoang, Bang H., Park, Amy, Fremed, Michael A., Zang, Xingxing, Gorlick, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960483/
https://www.ncbi.nlm.nih.gov/pubmed/27456063
http://dx.doi.org/10.1038/srep30093