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Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma
Osteosarcoma patient survival has remained stagnant for 30 years. Novel therapeutic approaches are needed to improve outcomes. We examined the expression of Programmed Death Ligand 1 (PD-L1) and defined the tumor immune microenvironment to assess the prognostic utility in osteosarcoma. PD-L1 express...
Autores principales: | Koirala, Pratistha, Roth, Michael E., Gill, Jonathan, Piperdi, Sajida, Chinai, Jordan M., Geller, David S., Hoang, Bang H., Park, Amy, Fremed, Michael A., Zang, Xingxing, Gorlick, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960483/ https://www.ncbi.nlm.nih.gov/pubmed/27456063 http://dx.doi.org/10.1038/srep30093 |
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