Loss-of-function screening to identify miRNAs involved in senescence: tumor suppressor activity of miRNA-335 and its new target CARF

Significance of microRNAs (miRs), small non-coding molecules, has been implicated in a variety of biological processes. Here, we recruited retroviral insertional mutagenesis to obtain induction of an arbitrary noncoding RNAs, and coupled it with a cell based loss-of-function (5-Aza-2′-deoxycytidine...

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Detalles Bibliográficos
Autores principales: Yu, Yue, Gao, Ran, Kaul, Zeenia, Li, Ling, Kato, Yoshio, Zhang, Zhenya, Groden, Joanna, Kaul, Sunil C, Wadhwa, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960484/
https://www.ncbi.nlm.nih.gov/pubmed/27457128
http://dx.doi.org/10.1038/srep30185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960484/
https://www.ncbi.nlm.nih.gov/pubmed/27457128
http://dx.doi.org/10.1038/srep30185

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