Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1

We previously demonstrated that ABCD4 does not localize to peroxisomes but rather, the endoplasmic reticulum (ER), because it lacks the NH(2)-terminal hydrophilic region required for peroxisomal targeting. It was recently reported that mutations in ABCD4 result in a failure to release vitamin B(12)...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Kosuke, Okamoto, Takumi, Morita, Masashi, Imanaka, Tsuneo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960490/
https://www.ncbi.nlm.nih.gov/pubmed/27456980
http://dx.doi.org/10.1038/srep30183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960490/
https://www.ncbi.nlm.nih.gov/pubmed/27456980
http://dx.doi.org/10.1038/srep30183

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