The ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux

Loss of anchorage to the extracellular matrix leads to apoptosis (anoikis) in normal cells, but cancerous cells are usually resistant to such stress. Here we report the pivotal role of an E3 ubiquitin ligase, ring-finger protein 126 (RNF126), in the resistance of cancer cells to the stress associate...

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Detalles Bibliográficos
Autores principales: Yoshino, Seiko, Hara, Toshiro, Nakaoka, Hiroki J, Kanamori, Akane, Murakami, Yoshinori, Seiki, Motoharu, Sakamoto, Takeharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960523/
https://www.ncbi.nlm.nih.gov/pubmed/27462466
http://dx.doi.org/10.1038/celldisc.2016.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960523/
https://www.ncbi.nlm.nih.gov/pubmed/27462466
http://dx.doi.org/10.1038/celldisc.2016.19

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