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Ligand binding to an Allergenic Lipid Transfer Protein Enhances Conformational Flexibility resulting in an Increase in Susceptibility to Gastroduodenal Proteolysis

Non-specific lipid transfer proteins (LTPs) are a family of lipid-binding molecules that are widely distributed across flowering plant species, many of which have been identified as allergens. They are highly resistant to simulated gastroduodenal proteolysis, a property that may play a role in deter...

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Detalles Bibliográficos
Autores principales: Abdullah, Syed Umer, Alexeev, Yuri, Johnson, Philip E., Rigby, Neil M., Mackie, Alan R., Dhaliwal, Balvinder, Mills, E. N. Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960534/
https://www.ncbi.nlm.nih.gov/pubmed/27458082
http://dx.doi.org/10.1038/srep30279