Vitamin D Deficiency Promotes Liver Tumor Growth in Transforming Growth Factor-β/Smad3-Deficient Mice Through Wnt and Toll-like Receptor 7 Pathway Modulation

Disruption of the TGF-β pathway is associated with liver fibrosis and suppression of liver tumorigenesis, conditions associated with low Vitamin D (VD) levels. However, potential contributions of VD to liver tumor progression in the context of TGF-β signaling remain unexplored. Our analyses of VD de...

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Detalles Bibliográficos
Autores principales: Chen, Jian, Katz, Lior H., Muñoz, Nina M., Gu, Shoujun, Shin, Ji-hyun, Jogunoori, Wilma S., Lee, Mi-Hye, Belkin, Mitchell D., Kim, Sang-Bae, White, Jon C., Andricovich, Jaclyn, Tzatsos, Alexandros, Li, Shulin, Kim, Sang Soo, Shetty, Kirti, Mishra, Bibhuti, Rashid, Asif, Lee, Ju-Seog, Mishra, Lopa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960540/
https://www.ncbi.nlm.nih.gov/pubmed/27456065
http://dx.doi.org/10.1038/srep30217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960540/
https://www.ncbi.nlm.nih.gov/pubmed/27456065
http://dx.doi.org/10.1038/srep30217

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