Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding

Shiga toxin (Stx), an AB(5) toxin, binds specifically to the neutral glycosphingolipid Gb3 at the cell surface before being transported into cells. We here demonstrate that addition of conical lysophospholipids (LPLs) with large head groups inhibit Stx binding to cells whereas LPLs with small head g...

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Detalles Bibliográficos
Autores principales: Ailte, Ieva, Lingelem, Anne Berit Dyve, Kavaliauskiene, Simona, Bergan, Jonas, Kvalvaag, Audun Sverre, Myrann, Anne-Grethe, Skotland, Tore, Sandvig, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960542/
https://www.ncbi.nlm.nih.gov/pubmed/27458147
http://dx.doi.org/10.1038/srep30336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960542/
https://www.ncbi.nlm.nih.gov/pubmed/27458147
http://dx.doi.org/10.1038/srep30336

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