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Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding
Shiga toxin (Stx), an AB(5) toxin, binds specifically to the neutral glycosphingolipid Gb3 at the cell surface before being transported into cells. We here demonstrate that addition of conical lysophospholipids (LPLs) with large head groups inhibit Stx binding to cells whereas LPLs with small head g...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960542/ https://www.ncbi.nlm.nih.gov/pubmed/27458147 http://dx.doi.org/10.1038/srep30336 |