Viperin inhibits rabies virus replication via reduced cholesterol and sphingomyelin and is regulated upstream by TLR4

Viperin (virus inhibitory protein, endoplasmic reticulum-associated, IFN-inducible) is an interferon-inducible protein that mediates antiviral activity. Generally, rabies virus (RABV) multiplies extremely well in susceptible cells, leading to high virus titres. In this study, we found that viperin w...

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Detalles Bibliográficos
Autores principales: Tang, Hai-Bo, Lu, Zhuan-Ling, Wei, Xian-Kai, Zhong, Tao-Zhen, Zhong, Yi-Zhi, Ouyang, Ling-Xuan, Luo, Yang, Xing, Xing-Wei, Liao, Fang, Peng, Ke-Ke, Deng, Chao-Qian, Minamoto, Nobuyuki, Luo, Ting Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960569/
https://www.ncbi.nlm.nih.gov/pubmed/27456665
http://dx.doi.org/10.1038/srep30529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960569/
https://www.ncbi.nlm.nih.gov/pubmed/27456665
http://dx.doi.org/10.1038/srep30529

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