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Viperin inhibits rabies virus replication via reduced cholesterol and sphingomyelin and is regulated upstream by TLR4
Viperin (virus inhibitory protein, endoplasmic reticulum-associated, IFN-inducible) is an interferon-inducible protein that mediates antiviral activity. Generally, rabies virus (RABV) multiplies extremely well in susceptible cells, leading to high virus titres. In this study, we found that viperin w...
Autores principales: | Tang, Hai-Bo, Lu, Zhuan-Ling, Wei, Xian-Kai, Zhong, Tao-Zhen, Zhong, Yi-Zhi, Ouyang, Ling-Xuan, Luo, Yang, Xing, Xing-Wei, Liao, Fang, Peng, Ke-Ke, Deng, Chao-Qian, Minamoto, Nobuyuki, Luo, Ting Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960569/ https://www.ncbi.nlm.nih.gov/pubmed/27456665 http://dx.doi.org/10.1038/srep30529 |
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