Changes in the folding landscape of the WW domain provide a molecular mechanism for an inherited genetic syndrome

WW domains are small domains present in many human proteins with a wide array of functions and acting through the recognition of proline-rich sequences. The WW domain belonging to polyglutamine tract-binding protein 1 (PQBP1) is of particular interest due to its direct involvement in several X chrom...

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Detalles Bibliográficos
Autores principales: Pucheta-Martinez, Encarna, D’Amelio, Nicola, Lelli, Moreno, Martinez-Torrecuadrada, Jorge L., Sudol, Marius, Saladino, Giorgio, Gervasio, Francesco Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960638/
https://www.ncbi.nlm.nih.gov/pubmed/27456546
http://dx.doi.org/10.1038/srep30293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960638/
https://www.ncbi.nlm.nih.gov/pubmed/27456546
http://dx.doi.org/10.1038/srep30293

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