Context-specific protection of TGFα null mice from osteoarthritis

Transforming growth factor alpha (TGFα) is a growth factor involved in osteoarthritis (OA). TGFα induces an OA-like phenotype in articular chondrocytes, by inhibiting matrix synthesis and promoting catabolic factor expression. To better understand TGFα’s potential as a therapeutic target, we employe...

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Detalles Bibliográficos
Autores principales: Usmani, Shirine E., Ulici, Veronica, Pest, Michael A., Hill, Tracy L., Welch, Ian D., Beier, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960644/
https://www.ncbi.nlm.nih.gov/pubmed/27457421
http://dx.doi.org/10.1038/srep30434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960644/
https://www.ncbi.nlm.nih.gov/pubmed/27457421
http://dx.doi.org/10.1038/srep30434

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