Cargando…
Local administration of siRNA through Microneedle: Optimization, Bio-distribution, Tumor Suppression and Toxicity
Although RNA interference may become a novel therapeutic approach for cancer treatment, target-site accumulation of siRNA to achieve therapeutic dosage will be a major problem. Microneedle represents a better way to deliver siRNAs and we have evaluated for the first time the capability of a silicon...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960650/ https://www.ncbi.nlm.nih.gov/pubmed/27457182 http://dx.doi.org/10.1038/srep30430 |