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Transcriptomic analyses of the radiation response in head and neck squamous cell carcinoma subclones with different radiation sensitivity: time-course gene expression profiles and gene association networks

BACKGROUND: Acquired and inherent radioresistance of tumor cells is related to tumor relapse and poor prognosis – not only in head and neck squamous cell carcinoma (HNSCC). The underlying molecular mechanisms are largely unknown. Therefore, systemic in-depth analyses are needed to identify key regul...

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Detalles Bibliográficos
Autores principales: Michna, Agata, Schötz, Ulrike, Selmansberger, Martin, Zitzelsberger, Horst, Lauber, Kirsten, Unger, Kristian, Hess, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960706/
https://www.ncbi.nlm.nih.gov/pubmed/27455841
http://dx.doi.org/10.1186/s13014-016-0672-0