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ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments

BACKGROUND: Cachexia affects the majority of patients with advanced cancer and is associated with reduced treatment tolerance, response to therapy, quality of life, and life expectancy. Cachectic patients with advanced cancer often receive anti-cancer therapies against their specific cancer type as...

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Detalles Bibliográficos
Autores principales: Hatakeyama, Shinji, Summermatter, Serge, Jourdain, Marie, Melly, Stefan, Minetti, Giulia C., Lach-Trifilieff, Estelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960708/
https://www.ncbi.nlm.nih.gov/pubmed/27462398
http://dx.doi.org/10.1186/s13395-016-0098-2