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Filaggrin gene mutations and new SNPs in asthmatic patients: a cross-sectional study in a Spanish population

BACKGROUND: Several null-mutations in the FLG gene that produce a decrease or absence of filaggrin in the skin and predispose to atopic dermatitis and ichthyosis vulgaris have been described. The relationship with asthma is less clear and may be due to the influence of atopy in patients with associa...

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Detalles Bibliográficos
Autores principales: Cubero, José Luis, Isidoro-García, María, Segura, Nieves, Benito Pescador, David, Sanz, Catalina, Lorente, Félix, Dávila, Ignacio, Colás, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960762/
https://www.ncbi.nlm.nih.gov/pubmed/27462351
http://dx.doi.org/10.1186/s13223-016-0137-x