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Modulation of endoglin expression in islets of langerhans by VEGF reveals a novel regulator of islet endothelial cell function

BACKGROUND: Endoglin/CD105 is an auxiliary receptor for transforming growth factor-β with established roles in vascular remodelling. It has recently been shown that heterozygous endoglin deficiency in mice decreases insulin secretion in an animal model of obesity, highlighting a potential role for e...

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Detalles Bibliográficos
Autores principales: Clarkin, Claire E., Mahmoud, Marwa, Liu, Bo, Sobamowo, Emmanuel O., King, Aileen, Arthur, Helen, Jones, Peter M., Wheeler-Jones, Caroline P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960785/
https://www.ncbi.nlm.nih.gov/pubmed/27456002
http://dx.doi.org/10.1186/s13104-016-2142-z