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The evolutionary scope and neurological disease linkage of yeast-prion-like proteins in humans

BACKGROUND: Prions are proteinaceous particles that propagate alternative protein conformations/states to further copies of the same proteins, and are transmitted from cell-to-cell, and organism-to-organism. Prions are usually made of the beta-sheet rich assemblies termed amyloid. The original prion...

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Detalles Bibliográficos
Autores principales: An, Lu, Harrison, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960796/
https://www.ncbi.nlm.nih.gov/pubmed/27457357
http://dx.doi.org/10.1186/s13062-016-0134-5