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The evolutionary scope and neurological disease linkage of yeast-prion-like proteins in humans
BACKGROUND: Prions are proteinaceous particles that propagate alternative protein conformations/states to further copies of the same proteins, and are transmitted from cell-to-cell, and organism-to-organism. Prions are usually made of the beta-sheet rich assemblies termed amyloid. The original prion...
Autores principales: | An, Lu, Harrison, Paul M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960796/ https://www.ncbi.nlm.nih.gov/pubmed/27457357 http://dx.doi.org/10.1186/s13062-016-0134-5 |
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