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Association of rs1137101 polymorphism in LEPR and susceptibility to knee osteoarthritis in a Northwest Chinese Han population

BACKGROUND: Osteoarthritis (OA) is a complex arthritic condition in which the genetic factor plays a crucial role. A single nucleotide polymorphism (SNP), rs1137101 (Gln223Arg) of leptin receptor (LEPR) gene has been demonstrated to be associated with susceptibility to knee OA. However, this associa...

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Detalles Bibliográficos
Autores principales: Yang, Jianhui, Du, Heng, Lv, Jianguo, Zhang, Lianhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960800/
https://www.ncbi.nlm.nih.gov/pubmed/27457563
http://dx.doi.org/10.1186/s12891-016-1162-0