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Utilizing native fluorescence imaging, modeling and simulation to examine pharmacokinetics and therapeutic regimen of a novel anticancer prodrug

BACKGROUND: Success of cancer prodrugs relying on a foreign gene requires specific delivery of the gene to the cancer, and improvements such as higher level gene transfer and expression. Attaining these objectives will be facilitated in preclinical studies using our newly discovered CNOB-GDEPT, cons...

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Detalles Bibliográficos
Autores principales: Wang, Jing-Hung, Endsley, Aaron N., Green, Carol E., Matin, A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960810/
https://www.ncbi.nlm.nih.gov/pubmed/27457630
http://dx.doi.org/10.1186/s12885-016-2508-6