Cargando…

A cohort analysis of men with a family history of BRCA1/2 and Lynch mutations for prostate cancer

BACKGROUND: Prostate cancer (PC) is a major health concern for men worldwide, with an estimated lifetime risk of ~14 %. A recent comprehensive analysis of mutational processes revealed ageing and mismatch repair as the only altered processes in PC. We wish to test if a cohort of men with inherited r...

Descripción completa

Detalles Bibliográficos
Autores principales: Kerr, Lynne, Rewhorn, Matthew J., Longmuir, Mark, Fraser, Sioban, Walsh, Shaun, Andrew, Nicola, Leung, Hing Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960816/
https://www.ncbi.nlm.nih.gov/pubmed/27456091
http://dx.doi.org/10.1186/s12885-016-2573-x