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Secondary structure impacts patterns of selection in human lncRNAs
BACKGROUND: Metazoans transcribe many long non-coding RNAs (lncRNAs) that are poorly conserved and whose function remains unknown. This has raised the questions of what fraction of the predicted lncRNAs is actually functional, and whether selection can effectively constrain lncRNAs in species with s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960838/ https://www.ncbi.nlm.nih.gov/pubmed/27457204 http://dx.doi.org/10.1186/s12915-016-0283-0 |