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Secondary structure impacts patterns of selection in human lncRNAs

BACKGROUND: Metazoans transcribe many long non-coding RNAs (lncRNAs) that are poorly conserved and whose function remains unknown. This has raised the questions of what fraction of the predicted lncRNAs is actually functional, and whether selection can effectively constrain lncRNAs in species with s...

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Detalles Bibliográficos
Autores principales: Pegueroles, Cinta, Gabaldón, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960838/
https://www.ncbi.nlm.nih.gov/pubmed/27457204
http://dx.doi.org/10.1186/s12915-016-0283-0

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