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Chronic Treatment with Ivabradine Does Not Affect Cardiovascular Autonomic Control in Rats

A low resting heart rate (HR) would be of great benefit in cardiovascular diseases. Ivabradine—a novel selective inhibitor of hyperpolarization-activated cyclic nucleotide gated (HCN) channels- has emerged as a promising HR lowering drug. Its effects on the autonomic HR control are little known. Thi...

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Detalles Bibliográficos
Autores principales: Silva, Fernanda C., Paiva, Franciny A., Müller-Ribeiro, Flávia C., Caldeira, Henrique M. A., Fontes, Marco A. P., de Menezes, Rodrigo C. A., Casali, Karina R., Fortes, Gláucia H., Tobaldini, Eleonora, Solbiati, Monica, Montano, Nicola, Dias Da Silva, Valdo J., Chianca, Deoclécio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960883/
https://www.ncbi.nlm.nih.gov/pubmed/27507948
http://dx.doi.org/10.3389/fphys.2016.00305