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Determinants of frequency-dependent regulation of Kv1.2-containing potassium channels

Voltage-gated potassium channels are important regulators of electrical excitation in many tissues, with Kv1.2 standing out as an essential contributor in the CNS. Genetic deletion of Kv1.2 invariably leads to early lethality in mice. In humans, mutations affecting Kv1.2 function are linked to epile...

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Detalles Bibliográficos
Autores principales: Baronas, Victoria A., Yang, Runying, Vilin, Yury Y., Kurata, Harley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960988/
https://www.ncbi.nlm.nih.gov/pubmed/26646078
http://dx.doi.org/10.1080/19336950.2015.1120390