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Spatial Genome Organization and Its Emerging Role as a Potential Diagnosis Tool
In eukaryotic cells the genome is highly spatially organized. Functional relevance of higher order genome organization is implied by the fact that specific genes, and even whole chromosomes, alter spatial position in concert with functional changes within the nucleus, for example with modifications...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961005/ https://www.ncbi.nlm.nih.gov/pubmed/27507988 http://dx.doi.org/10.3389/fgene.2016.00134 |