Harnessing the Endocannabinoid 2-Arachidonoylglycerol to Lower Intraocular Pressure in a Murine Model

PURPOSE: Cannabinoids, such as Δ(9)-THC, act through an endogenous signaling system in the vertebrate eye that reduces IOP via CB(1) receptors. Endogenous cannabinoid (eCB) ligand, 2-arachidonoyl glycerol (2-AG), likewise activates CB(1) and is metabolized by monoacylglycerol lipase (MAGL). We inves...

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Detalles Bibliográficos
Autores principales: Miller, Sally, Leishman, Emma, Hu, Sherry Shujung, Elghouche, Alhasan, Daily, Laura, Murataeva, Natalia, Bradshaw, Heather, Straiker, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961057/
https://www.ncbi.nlm.nih.gov/pubmed/27333182
http://dx.doi.org/10.1167/iovs.16-19356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961057/
https://www.ncbi.nlm.nih.gov/pubmed/27333182
http://dx.doi.org/10.1167/iovs.16-19356

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