Epigenetic Modification Prevents Excessive Wound Healing and Scar Formation After Glaucoma Filtration Surgery

PURPOSE: The purpose of this study was to determine the efficacy of suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor (HDACi), in prevention of excessive wound healing and scar formation in a rabbit model of glaucoma filtration surgery (GFS). METHODS: A rabbit model of GFS was...

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Detalles Bibliográficos
Autores principales: Sharma, Ajay, Anumanthan, Govindaraj, Reyes, Marcos, Chen, Huiyi, Brubaker, Jacob W., Siddiqui, Saad, Gupta, Suneel, Rieger, Frank G., Mohan, Rajiv R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961058/
https://www.ncbi.nlm.nih.gov/pubmed/27367506
http://dx.doi.org/10.1167/iovs.15-18750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961058/
https://www.ncbi.nlm.nih.gov/pubmed/27367506
http://dx.doi.org/10.1167/iovs.15-18750

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