Transcriptional Suppression of Renal Antioxidant Enzyme Systems in Guinea Pigs Exposed to Polymerized Cell-Free Hemoglobin

Hemoglobin-based oxygen carriers (HBOCs) are being developed as oxygen and plasma volume-expanding therapeutics though their potential to promote oxidative tissue injury has raised safety concerns. Using a guinea pig exchange transfusion model, we examined the effects of polymerized bovine hemoglobi...

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Detalles Bibliográficos
Autores principales: Rentsendorj, Otgonchimeg, Zhang, Xiaoyuan, Williams, Matthew C., Buehler, Paul W., D’Agnillo, Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961095/
https://www.ncbi.nlm.nih.gov/pubmed/27471729
http://dx.doi.org/10.3390/toxics4010006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961095/
https://www.ncbi.nlm.nih.gov/pubmed/27471729
http://dx.doi.org/10.3390/toxics4010006

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