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Tumor-infiltrating monocytes/macrophages promote tumor invasion and migration by upregulating S100A8 and S100A9 expression in cancer cells

Myeloid cells promote the development of distant metastases, but little is known about the molecular mechanisms underlying this process. Here we have begun to uncover the effects of myeloid cells on cancer cells in a mouse model of liver metastasis. Monocytes/macrophages, but not granulocytes, isola...

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Detalles Bibliográficos
Autores principales: Lim, S Y, Yuzhalin, A E, Gordon-Weeks, A N, Muschel, R J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961254/
https://www.ncbi.nlm.nih.gov/pubmed/27086923
http://dx.doi.org/10.1038/onc.2016.107