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Effects of Obesity on Perivascular Adipose Tissue Vasorelaxant Function: Nitric Oxide, Inflammation and Elevated Systemic Blood Pressure

INTRODUCTION: Perivascular adipose tissue (PVAT) surrounds most vessels in the human body. Healthy PVAT has a vasorelaxant effect which is not observed in obesity. We assessed the contribution of nitric oxide (NO), inflammation and endothelium to obesity-induced PVAT damage. METHODS: Rats were fed a...

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Detalles Bibliográficos
Autores principales: Aghamohammadzadeh, Reza, Unwin, Richard D., Greenstein, Adam S., Heagerty, Anthony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961268/
https://www.ncbi.nlm.nih.gov/pubmed/26910225
http://dx.doi.org/10.1159/000443885