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Influence of SULT1A1 genetic variation on age at menopause, estrogen levels, and response to hormone therapy in recently postmenopausal white women

OBJECTIVE: Onset and symptoms of menopause, and response to hormone therapy (HT) show large interindividual variability. SULT1A1 encodes for a highly expressed enzyme that metabolizes estrogens. We evaluated the relationship between genetic variation in SULT1A1, menopause age, symptoms, and response...

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Detalles Bibliográficos
Autores principales: Moyer, Ann M., de Andrade, Mariza, Weinshilboum, Richard M., Miller, Virginia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott-Raven Publishers 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961269/
https://www.ncbi.nlm.nih.gov/pubmed/27300114
http://dx.doi.org/10.1097/GME.0000000000000648