Cargando…

CD103(+) Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans

Innate immune cells shape the host response to microbial pathogens. Here we elucidate critical differences in the molecular response of macrophages vs. dendritic cells (DCs) to Histoplasma capsulatum, an intracellular fungal pathogen of humans. It has long been known that macrophages are permissive...

Descripción completa

Detalles Bibliográficos
Autores principales: Van Prooyen, Nancy, Henderson, C. Allen, Hocking Murray, Davina, Sil, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961300/
https://www.ncbi.nlm.nih.gov/pubmed/27459510
http://dx.doi.org/10.1371/journal.ppat.1005749