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CD103(+) Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans
Innate immune cells shape the host response to microbial pathogens. Here we elucidate critical differences in the molecular response of macrophages vs. dendritic cells (DCs) to Histoplasma capsulatum, an intracellular fungal pathogen of humans. It has long been known that macrophages are permissive...
Autores principales: | Van Prooyen, Nancy, Henderson, C. Allen, Hocking Murray, Davina, Sil, Anita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961300/ https://www.ncbi.nlm.nih.gov/pubmed/27459510 http://dx.doi.org/10.1371/journal.ppat.1005749 |
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