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A biphasic effect of TNF-α in regulation of the Keap1/Nrf2 pathway in cardiomyocytes

Antagonizing TNF-α signaling attenuates chronic inflammatory disease, but is associated with adverse effects on the cardiovascular system. Therefore the impact of TNF-α on basal control of redox signaling events needs to be understand in more depth. This is particularly important for the Keap1/Nrf2...

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Detalles Bibliográficos
Autores principales: Shanmugam, Gobinath, Narasimhan, Madhusudhanan, Sakthivel, Ramasamy, Kumar R, Rajesh, Davidson, Christopher, Palaniappan, Sethu, Claycomb, William W., Hoidal, John R., Darley-Usmar, Victor M., Rajasekaran, Namakkal Soorappan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961303/
https://www.ncbi.nlm.nih.gov/pubmed/27423013
http://dx.doi.org/10.1016/j.redox.2016.06.004