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A biphasic effect of TNF-α in regulation of the Keap1/Nrf2 pathway in cardiomyocytes
Antagonizing TNF-α signaling attenuates chronic inflammatory disease, but is associated with adverse effects on the cardiovascular system. Therefore the impact of TNF-α on basal control of redox signaling events needs to be understand in more depth. This is particularly important for the Keap1/Nrf2...
Autores principales: | Shanmugam, Gobinath, Narasimhan, Madhusudhanan, Sakthivel, Ramasamy, Kumar R, Rajesh, Davidson, Christopher, Palaniappan, Sethu, Claycomb, William W., Hoidal, John R., Darley-Usmar, Victor M., Rajasekaran, Namakkal Soorappan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961303/ https://www.ncbi.nlm.nih.gov/pubmed/27423013 http://dx.doi.org/10.1016/j.redox.2016.06.004 |
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