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The Phospholipid:Diacylglycerol Acyltransferase Lro1 Is Responsible for Hepatitis C Virus Core-Induced Lipid Droplet Formation in a Yeast Model System

Chronic infection with the hepatitis C virus frequently induces steatosis, which is a significant risk factor for liver pathogenesis. Steatosis is characterized by the accumulation of lipid droplets in hepatocytes. The structural protein core of the virus induces lipid droplet formation and localize...

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Detalles Bibliográficos
Autores principales: Iwasa, Shingo, Sato, Naoko, Wang, Chao-Wen, Cheng, Yun-Hsin, Irokawa, Hayato, Hwang, Gi-Wook, Naganuma, Akira, Kuge, Shusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961368/
https://www.ncbi.nlm.nih.gov/pubmed/27459103
http://dx.doi.org/10.1371/journal.pone.0159324