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The Phospholipid:Diacylglycerol Acyltransferase Lro1 Is Responsible for Hepatitis C Virus Core-Induced Lipid Droplet Formation in a Yeast Model System
Chronic infection with the hepatitis C virus frequently induces steatosis, which is a significant risk factor for liver pathogenesis. Steatosis is characterized by the accumulation of lipid droplets in hepatocytes. The structural protein core of the virus induces lipid droplet formation and localize...
Autores principales: | Iwasa, Shingo, Sato, Naoko, Wang, Chao-Wen, Cheng, Yun-Hsin, Irokawa, Hayato, Hwang, Gi-Wook, Naganuma, Akira, Kuge, Shusuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961368/ https://www.ncbi.nlm.nih.gov/pubmed/27459103 http://dx.doi.org/10.1371/journal.pone.0159324 |
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