Multiscale Simulations Suggest a Mechanism for the Association of the Dok7 PH Domain with PIP-Containing Membranes

Dok7 is a peripheral membrane protein that is associated with the MuSK receptor tyrosine kinase. Formation of the Dok7/MuSK/membrane complex is required for the activation of MuSK. This is a key step in the complex exchange of signals between neuron and muscle, which lead to neuromuscular junction f...

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Detalles Bibliográficos
Autores principales: Buyan, Amanda, Kalli, Antreas C., Sansom, Mark S. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961371/
https://www.ncbi.nlm.nih.gov/pubmed/27459095
http://dx.doi.org/10.1371/journal.pcbi.1005028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961371/
https://www.ncbi.nlm.nih.gov/pubmed/27459095
http://dx.doi.org/10.1371/journal.pcbi.1005028

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