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Structure of Alcohol Oxidase from Pichia pastoris by Cryo-Electron Microscopy

The first step in methanol metabolism in methylotrophic yeasts, the oxidation of methanol and higher alcohols with molecular oxygen to formaldehyde and hydrogen peroxide, is catalysed by alcohol oxidase (AOX), a 600-kDa homo-octamer containing eight FAD cofactors. When these yeasts are grown with me...

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Detalles Bibliográficos
Autores principales: Vonck, Janet, Parcej, David N., Mills, Deryck J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961394/
https://www.ncbi.nlm.nih.gov/pubmed/27458710
http://dx.doi.org/10.1371/journal.pone.0159476