The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment

Understanding how differentiation programs originate from within the gene expression landscape of hematopoietic stem cells (HSC) is crucial to develop new clinical therapies. We mapped the transcriptional dynamics underlying the first steps of commitment by tracking transcriptome changes in human HS...

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Detalles Bibliográficos
Autores principales: Laurenti, Elisa, Doulatov, Sergei, Zandi, Sasan, Plumb, Ian, Chen, Jing, April, Craig, Fan, Jian-Bing, Dick, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961471/
https://www.ncbi.nlm.nih.gov/pubmed/23708252
http://dx.doi.org/10.1038/ni.2615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961471/
https://www.ncbi.nlm.nih.gov/pubmed/23708252
http://dx.doi.org/10.1038/ni.2615

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